A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the Upholstered Full Bed right maxilla with a cytoreductive surgery followed by a definitive radiation protocol.Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor.Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing Acne Treatment odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid.
This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.